Airway inflammation can cause people with asthma to have persistent symptoms of coughing, wheezing, chest tightness, and shortness of breath. They may also experience a flare-up or asthma "attack."

While asthma is commonly known to affect the large airways, many recent asthma studies have shown how inflammation of the small airways contributes to asthma symptoms too. If a long-term control medicine does not reach or treat both the large and small airways, underlying chronic inflammation may persist.

There are many irritants in the air, like bacteria, pollen and dust. People with asthma can be more sensitive to these irritants, or triggers, and their immune systems can overreact by releasing different cells and chemicals into the airways causing inflammation.

Chronic Inflammation

Over time, people with asthma can develop chronic inflammation that makes the airways even more sensitive. If the inflammation is not treated properly, each time a person with asthma is exposed to triggers, inflammation can increase, and the airways can constrict and become blocked with mucus. This can result in an increased chance of an asthma attack.

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